张天成

博士、上海市生物医药技术研究院副研究员

主要研究方向∶1、精子特异蛋白在早期胚胎发育过程中的功能及机制;2、精子特异蛋白用于肿瘤早期诊断的研究。

发表论文∶1、LiuM，RuY，GuY，TangJ，ZhangT，WuJ，YuF，YuanY，XuC，WangJ*，ShiH* . Disruption of Ssp411 causes impaired sperm head formation and male sterility in mice. Biochim Biophys Acta.2018 Mar;1862(3):660-668.

2、ShenJ#，MaH#，ZhangT#，LiuH，YuL，LiG，LiH，HuM* Magnolol Inhibits the Growth of Non-Small Cell Lung Cancer via Inhibiting Microtubule Polymerization. Cell Physiol Biochem. 2017;42(5):1789-1801.

3、NiZ,Zhang TC* Computationally unraveling how ceritinib overcomes drug-resistance mutations in ALK-rearranged lung cancer. J Mol Model. 2015 Jul;21(7):175.

4、NiZ, WangX ,Zhang T, Jin RZ.Molecular dynamics simulations reveal the allosteric effect of F1174C resistance mutation to ceritinib in ALK-associated lung cancer. Comput Biol Chem.2016 Dec;65:54-60.

5、ZHONG NI,XITING WANG,TIANCHEN ZHANG,LINLIN LI and JIANXUE LI Comprehensive analysis of differential expression profiles reveals potential biomarkers associated with the cell cycle and regulated by p53 in human small cell lung cancer. EXPERIMENTALAND THERAPEUTIC MEDICNE 15:3273-3282,2018

6、TIANCHENG ZHANG,JUN WU,CAIHUA LIAO,ZHONG NI，JUFEN ZHENG，and FUDONG YU System analysis of teratozoospermia mRNAprofile based on integrated bioinformatics tools MOLECULAR MEDICINE REPORTS 18:1297-1304, 2018